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Energy efficiency trade-offs drive nucleotide usage in transcribed regions

Efficient nutrient usage is a trait under universal selection. A substantial part of cellular resources is spent on making nucleotides. We thus expect preferential use of cheaper nucleotides especially in transcribed sequences, which are often amplified thousand-fold compared with genomic sequences....

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Detalles Bibliográficos
Autores principales: Chen, Wei-Hua, Lu, Guanting, Bork, Peer, Hu, Songnian, Lercher, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844684/
https://www.ncbi.nlm.nih.gov/pubmed/27098217
http://dx.doi.org/10.1038/ncomms11334