Untangling the brain's neuroinflammatory and neurodegenerative transcriptional responses

A common approach to understanding neurodegenerative disease is comparing gene expression in diseased versus healthy tissues. We illustrate that expression profiles derived from whole tissue RNA highly reflect the degenerating tissues' altered cellular composition, not necessarily transcription...

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Detalles Bibliográficos
Autores principales: Srinivasan, Karpagam, Friedman, Brad A., Larson, Jessica L., Lauffer, Benjamin E., Goldstein, Leonard D., Appling, Laurie L., Borneo, Jovencio, Poon, Chungkee, Ho, Terence, Cai, Fang, Steiner, Pascal, van der Brug, Marcel P., Modrusan, Zora, Kaminker, Joshua S., Hansen, David V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844685/
https://www.ncbi.nlm.nih.gov/pubmed/27097852
http://dx.doi.org/10.1038/ncomms11295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844685/
https://www.ncbi.nlm.nih.gov/pubmed/27097852
http://dx.doi.org/10.1038/ncomms11295

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