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Copper-catalyzed enantioselective stereodivergent synthesis of amino alcohols
The chirality, or ‘handedness’, of a biologically active molecule can alter its physiological properties. For this reason, it is routine procedure in the drug discovery and development process to prepare and fully characterize all possible stereoisomers of a drug candidate for biological evaluation(...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844805/ https://www.ncbi.nlm.nih.gov/pubmed/27018656 http://dx.doi.org/10.1038/nature17191 |