Ghrelin Protects against Dexamethasone-Induced INS-1 Cell Apoptosis via ERK and p38MAPK Signaling

Glucocorticoid excess induces apoptosis of islet cells, which may result in diabetes. In this study, we investigated the protective effect of ghrelin on dexamethasone-induced INS-1 cell apoptosis. Our data showed that ghrelin (0.1 μM) inhibited dexamethasone-induced (0.1 μM) apoptosis of INS-1 cells...

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Detalles Bibliográficos
Autores principales: Zhang, Chengshuo, Li, Le, Zhao, Bochao, Jiao, Ao, Li, Xin, Sun, Ning, Zhang, Jialin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844876/
https://www.ncbi.nlm.nih.gov/pubmed/27190513
http://dx.doi.org/10.1155/2016/4513051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844876/
https://www.ncbi.nlm.nih.gov/pubmed/27190513
http://dx.doi.org/10.1155/2016/4513051

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