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Role of Striatal-Enriched Tyrosine Phosphatase in Neuronal Function

Striatal-enriched protein tyrosine phosphatase (STEP) is a CNS-enriched protein implicated in multiple neurologic and neuropsychiatric disorders. STEP regulates key signaling proteins required for synaptic strengthening as well as NMDA and AMPA receptor trafficking. Both high and low levels of STEP...

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Detalles Bibliográficos
Autores principales: Kamceva, Marija, Benedict, Jessie, Nairn, Angus C., Lombroso, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844879/
https://www.ncbi.nlm.nih.gov/pubmed/27190655
http://dx.doi.org/10.1155/2016/8136925