Cargando…

Dual Regulation of R-Type Ca(V)2.3 Channels by M(1) Muscarinic Receptors

Voltage-gated Ca(2+) (Ca(V)) channels are dynamically modulated by G protein-coupled receptors (GPCR). The M(1) muscarinic receptor stimulation is known to enhance Ca(V)2.3 channel gating through the activation of protein kinase C (PKC). Here, we found that M(1) receptors also inhibit Ca(V)2.3 curre...

Descripción completa

Detalles Bibliográficos
Autores principales: Jeong, Jin-Young, Kweon, Hae-Jin, Suh, Byung-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844939/
https://www.ncbi.nlm.nih.gov/pubmed/26923189
http://dx.doi.org/10.14348/molcells.2016.2292