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A biofidelic 3D culture model to study the development of brain cellular systems

Little is known about how cells assemble as systems during corticogenesis to generate collective functions. We built a neurobiology platform that consists of fetal rat cerebral cortical cells grown within 3D silk scaffolds (SF). Ivermectin (Ivm), a glycine receptor (GLR) agonist, was used to modulat...

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Detalles Bibliográficos
Autores principales: Ren, M., Du, C., Herrero Acero, E., Tang-Schomer, M. D., Özkucur, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844952/
https://www.ncbi.nlm.nih.gov/pubmed/27112667
http://dx.doi.org/10.1038/srep24953