IL-13 mediates collagen deposition via STAT6 and microRNA-135b: a role for epigenetics

Systemic sclerosis is an autoimmune connective tissue disease in which T cells play a prominent role. We and others have previously demonstrated a role for T cell-derived IL-13 in mediating the induction of collagen in dermal fibroblasts and that blockade with IL-13 antibodies attenuates this increa...

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Detalles Bibliográficos
Autores principales: O’Reilly, Steven, Ciechomska, Marzena, Fullard, Nicola, Przyborski, Stefan, van Laar, Jacob M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844987/
https://www.ncbi.nlm.nih.gov/pubmed/27113293
http://dx.doi.org/10.1038/srep25066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844987/
https://www.ncbi.nlm.nih.gov/pubmed/27113293
http://dx.doi.org/10.1038/srep25066

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