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Combining measurements to estimate properties and characterization extent of complex biochemical mixtures; applications to Heparan Sulfate

Complex mixtures of molecular species, such as glycoproteins and glycosaminoglycans, have important biological and therapeutic functions. Characterization of these mixtures with analytical chemistry measurements is an important step when developing generic drugs such as biosimilars. Recent developme...

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Detalles Bibliográficos
Autores principales: Pradines, Joël R., Beccati, Daniela, Lech, Miroslaw, Ozug, Jennifer, Farutin, Victor, Huang, Yongqing, Gunay, Nur Sibel, Capila, Ishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845011/
https://www.ncbi.nlm.nih.gov/pubmed/27112127
http://dx.doi.org/10.1038/srep24829