Hypomethylation of ERVs in the sperm of mice haploinsufficient for the histone methyltransferase Setdb1 correlates with a paternal effect on phenotype

The number of reports of paternal epigenetic influences on the phenotype of offspring in rodents is increasing but the molecular events involved remain unclear. Here, we show that haploinsufficiency for the histone 3 lysine 9 methyltransferase Setdb1 in the sire can influence the coat colour phenoty...

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Detalles Bibliográficos
Autores principales: Daxinger, Lucia, Oey, Harald, Isbel, Luke, Whitelaw, Nadia C., Youngson, Neil A., Spurling, Alex, Vonk, Kelly K. D., Whitelaw, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845014/
https://www.ncbi.nlm.nih.gov/pubmed/27112447
http://dx.doi.org/10.1038/srep25004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845014/
https://www.ncbi.nlm.nih.gov/pubmed/27112447
http://dx.doi.org/10.1038/srep25004

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