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Rifampin Regulation of Drug Transporters Gene Expression and the Association of MicroRNAs in Human Hepatocytes

Membrane drug transporters contribute to the disposition of many drugs. In human liver, drug transport is controlled by two main superfamilies of transporters, the solute carrier transporters (SLC) and the ATP Binding Cassette transporters (ABC). Altered expression of these transporters due to drug-...

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Detalles Bibliográficos
Autores principales: Benson, Eric A., Eadon, Michael T., Desta, Zeruesenay, Liu, Yunlong, Lin, Hai, Burgess, Kimberly S., Segar, Matthew W., Gaedigk, Andrea, Skaar, Todd C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845040/
https://www.ncbi.nlm.nih.gov/pubmed/27199754
http://dx.doi.org/10.3389/fphar.2016.00111