Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan

Cellular senescence, a stress-induced irreversible growth arrest often characterized by p16(Ink4a) expression and a distinctive secretory phenotype, prevents the proliferation of preneoplastic cells and has beneficial roles in tissue remodelling during embryogenesis and wound healing. Senescent cell...

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Detalles Bibliográficos
Autores principales: Baker, Darren J., Childs, Bennett G., Durik, Matej, Wijers, Melinde E., Sieben, Cynthia J., Zhong, Jian, Saltness, Rachel, Jeganathan, Karthik B., Versoza, Grace C., Pezeshki, Abdul-Mohammad, Khazaie, Khashayarsha, Miller, Jordan D., van Deursen, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845101/
https://www.ncbi.nlm.nih.gov/pubmed/26840489
http://dx.doi.org/10.1038/nature16932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845101/
https://www.ncbi.nlm.nih.gov/pubmed/26840489
http://dx.doi.org/10.1038/nature16932

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