Myristoylated Alanine‐Rich Protein Kinase Substrate (MARCKS) Regulates Small GTPase Rac1 and Cdc42 Activity and Is a Critical Mediator of Vascular Smooth Muscle Cell Migration in Intimal Hyperplasia Formation

BACKGROUND: Transcription of the myristoylated alanine‐rich C kinase substrate (MARCKS) is upregulated in animal models of intimal hyperplasia. MARCKS knockdown inhibits vascular smooth muscle cell (VSMC) migration in vitro; however, the mechanism is as yet unknown. We sought to elucidate the mechan...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Dan, Makkar, George, Strickland, Dudley K., Blanpied, Thomas A., Stumpo, Deborah J., Blackshear, Perry J., Sarkar, Rajabrata, Monahan, Thomas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845127/
https://www.ncbi.nlm.nih.gov/pubmed/26450120
http://dx.doi.org/10.1161/JAHA.115.002255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845127/
https://www.ncbi.nlm.nih.gov/pubmed/26450120
http://dx.doi.org/10.1161/JAHA.115.002255

Ejemplares similares