Identification of a Novel Heart–Liver Axis: Matrix Metalloproteinase‐2 Negatively Regulates Cardiac Secreted Phospholipase A(2) to Modulate Lipid Metabolism and Inflammation in the Liver

BACKGROUND: Endocrine functions of the heart have been well established. We investigated the hypothesis that cardiac secretion of a unique phospholipase A(2) recently identified by our laboratory (cardiac secreted phospholipase A(2) [sPLA (2)]) establishes a heart–liver endocrine axis that is negati...

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Detalles Bibliográficos
Autores principales: Hernandez‐Anzaldo, Samuel, Berry, Evan, Brglez, Vesna, Leung, Dickson, Yun, Tae Jin, Lee, Jun Seong, Filep, Janos G., Kassiri, Zamaneh, Cheong, Cheolho, Lambeau, Gérard, Lehner, Richard, Fernandez‐Patron, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845223/
https://www.ncbi.nlm.nih.gov/pubmed/26567374
http://dx.doi.org/10.1161/JAHA.115.002553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845223/
https://www.ncbi.nlm.nih.gov/pubmed/26567374
http://dx.doi.org/10.1161/JAHA.115.002553

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