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Elevated Transglutaminase Activity Triggers Angiotensin Receptor Activating Autoantibody Production and Pathophysiology of Preeclampsia

BACKGROUND: Preeclampsia (PE) is a life‐threatening hypertensive disorder of pregnancy associated with autoantibodies, termed AT (1)‐AA, that activate the AT (1) angiotensin receptor. Although the pathogenic nature of these autoantibodies has been extensively studied, little is known about the molec...

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Detalles Bibliográficos
Autores principales: Liu, Chen, Luo, Renna, Elliott, Serra E., Wang, Wei, Parchim, Nicholas F., Iriyama, Takayuki, Daugherty, Patrick S., Blackwell, Sean C., Sibai, Baha M., Kellems, Rodney E., Xia, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845265/
https://www.ncbi.nlm.nih.gov/pubmed/26675250
http://dx.doi.org/10.1161/JAHA.115.002323