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Elevated Transglutaminase Activity Triggers Angiotensin Receptor Activating Autoantibody Production and Pathophysiology of Preeclampsia
BACKGROUND: Preeclampsia (PE) is a life‐threatening hypertensive disorder of pregnancy associated with autoantibodies, termed AT (1)‐AA, that activate the AT (1) angiotensin receptor. Although the pathogenic nature of these autoantibodies has been extensively studied, little is known about the molec...
Autores principales: | Liu, Chen, Luo, Renna, Elliott, Serra E., Wang, Wei, Parchim, Nicholas F., Iriyama, Takayuki, Daugherty, Patrick S., Blackwell, Sean C., Sibai, Baha M., Kellems, Rodney E., Xia, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845265/ https://www.ncbi.nlm.nih.gov/pubmed/26675250 http://dx.doi.org/10.1161/JAHA.115.002323 |
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