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EZH2 overexpression in different immunophenotypes of breast carcinoma and association with clinicopathologic features

BACKGROUND: Enhancer of zest homolog 2 (EZH2), a histone 3 methyltransferase, is associated with aggressive behavior of many tumors and is a promising target of molecular therapy. METHODS: To better elucidate the relevance of EZH2 in breast cancer subtypes, we evaluated EZH2 expression in 226 invasi...

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Detalles Bibliográficos
Autores principales: Guo, Shuangping, Li, Xia, Rohr, Joseph, Wang, Yingmei, Ma, Shirong, Chen, Peng, Wang, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845361/
https://www.ncbi.nlm.nih.gov/pubmed/27113214
http://dx.doi.org/10.1186/s13000-016-0491-5