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Integrative analysis of the Trypanosoma brucei gene expression cascade predicts differential regulation of mRNA processing and unusual control of ribosomal protein expression

BACKGROUND: Trypanosoma brucei is a unicellular parasite which multiplies in mammals (bloodstream form) and Tsetse flies (procyclic form). Trypanosome RNA polymerase II transcription is polycistronic, individual mRNAs being excised by trans splicing and polyadenylation. We previously made detailed m...

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Detalles Bibliográficos
Autores principales: Antwi, Enoch B., Haanstra, Jurgen R., Ramasamy, Gowthaman, Jensen, Bryan, Droll, Dorothea, Rojas, Federico, Minia, Igor, Terrao, Monica, Mercé, Clémentine, Matthews, Keith, Myler, Peter J., Parsons, Marilyn, Clayton, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845500/
https://www.ncbi.nlm.nih.gov/pubmed/27118143
http://dx.doi.org/10.1186/s12864-016-2624-3