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Integrative analysis of the Trypanosoma brucei gene expression cascade predicts differential regulation of mRNA processing and unusual control of ribosomal protein expression
BACKGROUND: Trypanosoma brucei is a unicellular parasite which multiplies in mammals (bloodstream form) and Tsetse flies (procyclic form). Trypanosome RNA polymerase II transcription is polycistronic, individual mRNAs being excised by trans splicing and polyadenylation. We previously made detailed m...
Autores principales: | Antwi, Enoch B., Haanstra, Jurgen R., Ramasamy, Gowthaman, Jensen, Bryan, Droll, Dorothea, Rojas, Federico, Minia, Igor, Terrao, Monica, Mercé, Clémentine, Matthews, Keith, Myler, Peter J., Parsons, Marilyn, Clayton, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845500/ https://www.ncbi.nlm.nih.gov/pubmed/27118143 http://dx.doi.org/10.1186/s12864-016-2624-3 |
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