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Characterization of a Novel Anti-Human HB-EGF Monoclonal Antibody Applicable for Paraffin-Embedded Tissues and Diagnosis of HB-EGF-Related Cancers

Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of growth factors that bind to and activate the EGF receptor (EGFR/ErbB1) and ErbB4. HB-EGF plays pivotal roles in pathophysiological processes, including cancer. Thus, monoclonal antibodies (mAbs) for HB-EGF detection cou...

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Detalles Bibliográficos
Autores principales: Iwamoto, Ryo, Takagi, Mika, Akatsuka, Jun-ichi, Ono, Ken-ichiro, Kishi, Yoshiro, Mekada, Eisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845685/
https://www.ncbi.nlm.nih.gov/pubmed/26974561
http://dx.doi.org/10.1089/mab.2015.0062