Cargando…

Characterization of a Novel Anti-Human HB-EGF Monoclonal Antibody Applicable for Paraffin-Embedded Tissues and Diagnosis of HB-EGF-Related Cancers

Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of growth factors that bind to and activate the EGF receptor (EGFR/ErbB1) and ErbB4. HB-EGF plays pivotal roles in pathophysiological processes, including cancer. Thus, monoclonal antibodies (mAbs) for HB-EGF detection cou...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iwamoto, Ryo, Takagi, Mika, Akatsuka, Jun-ichi, Ono, Ken-ichiro, Kishi, Yoshiro, Mekada, Eisuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc. 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845685/ https://www.ncbi.nlm.nih.gov/pubmed/26974561 http://dx.doi.org/10.1089/mab.2015.0062

Ejemplares similares

Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities
por: Yamazaki, Satoru, et al.
Publicado: (2003)

A Potent Anti-HB-EGF Monoclonal Antibody Inhibits Cancer Cell Proliferation and Multiple Angiogenic Activities of HB-EGF
por: Sato, Shuji, et al.
Publicado: (2012)

Identification of the Cancer Cell Proliferation and Survival Functions of proHB-EGF by Using an Anti-HB-EGF Antibody
por: Sato, Shuji, et al.
Publicado: (2013)

Correlation of IL-1 and HB-EGF with endometrial receptivity
por: Wang, Hui, et al.
Publicado: (2018)

APF, HB-EGF, and EGF biomarkers in patients with ulcerative vs. non-ulcerative interstitial cystitis
por: Zhang, Chen-Ou, et al.
Publicado: (2005)

Excess HB-EGF, which promotes VEGF signaling, leads to hydrocephalus
por: Shim, Joon W., et al.
Publicado: (2016)

HB-EGF Ameliorates Oxidative Stress-Mediated Uterine Decidualization Damage
por: Yu, Hai-Fan, et al.
Publicado: (2019)

Malignant pleural mesothelioma and epidermal growth factor receptor (EGF-R). Relationship of EGF-R with histology and survival using fixed paraffin embedded tissue and the F4, monoclonal antibody.
por: Dazzi, H., et al.
Publicado: (1990)

Small GTP‐binding protein Rap1 mediates EGF and HB‐EGF signaling and modulates EGF receptor expression in HTR‐8/SVneo extravillous trophoblast cells
por: Yoshie, Mikihiro, et al.
Publicado: (2023)

Nuclear translocation of the cytoplasmic domain of HB-EGF induces gastric cancer invasion
por: Shimura, Takaya, et al.
Publicado: (2012)

Myeloid Cell-Derived HB-EGF Drives Tissue Recovery After Pancreatitis
por: Wen, Hui-Ju, et al.
Publicado: (2019)

An unanticipated discourse of HB-EGF with VANGL2 signaling during embryo implantation
por: Kim, Yeon Sun, et al.
Publicado: (2023)

Expression of PRB, FKBP52 and HB-EGF Relating with Ultrasonic Evaluation of Endometrial Receptivity
por: Wang, Ning, et al.
Publicado: (2012)

Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia
por: Díaz, Begoña, et al.
Publicado: (2013)

Discovery of HB-EGF binding peptides and their functional characterization in ovarian cancer cell lines
por: Shen, Yanting, et al.
Publicado: (2019)

M2 macrophages reduce the radiosensitivity of head and neck cancer by releasing HB-EGF
por: Fu, Enhui, et al.
Publicado: (2020)

HB-EGF Signaling Is Required for Glucose-Induced Pancreatic β-Cell Proliferation in Rats
por: Maachi, Hasna, et al.
Publicado: (2020)

Roles for HB‐EGF in Mesenchymal Stromal Cell Proliferation and Differentiation During Skeletal Growth
por: Li, Ping, et al.
Publicado: (2018)

Helicobacter pylori-Induced HB-EGF Upregulates Gastrin Expression via the EGF Receptor, C-Raf, Mek1, and Erk2 in the MAPK Pathway
por: Gunawardhana, Niluka, et al.
Publicado: (2018)

Membrane-anchored growth factor, HB-EGF, on the cell surface targeted to the inner nuclear membrane
por: Hieda, Miki, et al.
Publicado: (2008)

Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF
por: Nanba, Daisuke, et al.
Publicado: (2003)

Restraint Stress Inhibits Mouse Implantation: Temporal Window and the Involvement of HB-EGF, Estrogen and Progesterone
por: Zhao, Li-Hua, et al.
Publicado: (2013)

NGF and HB-EGF: Potential Biomarkers that Reflect the Effects of Fesoterodine in Patients with Overactive Bladder Syndrome
por: Kim, Soo Rim, et al.
Publicado: (2015)

DSE promotes aggressive glioma cell phenotypes by enhancing HB-EGF/ErbB signaling
por: Liao, Wen-Chieh, et al.
Publicado: (2018)

High levels of HB-EGF and interleukin-18 are associated with a high risk of in-stent restenosis
por: Jiang, Hua, et al.
Publicado: (2016)

Elevated murine HB-EGF confers sensitivity to diphtheria toxin in EGFR-mutant lung adenocarcinoma
por: Robles-Oteiza, Camila, et al.
Publicado: (2021)

Targeting hepatic heparin-binding EGF-like growth factor (HB-EGF) induces anti-hyperlipidemia leading to reduction of angiotensin II-induced aneurysm development
por: Kim, Seonwook, et al.
Publicado: (2017)

Control of Human Endometrial Stromal Cell Motility by PDGF-BB, HB-EGF and Trophoblast-Secreted Factors
por: Schwenke, Maren, et al.
Publicado: (2013)

H(2)S restores the cardioprotective effects of ischemic post-conditioning by upregulating HB-EGF/EGFR signaling
por: Zhang, Yuanzhou, et al.
Publicado: (2019)

HB-EGF–EGFR Signaling in Bone Marrow Endothelial Cells Mediates Angiogenesis Associated with Multiple Myeloma
por: Rao, Luigia, et al.
Publicado: (2020)

EGF and HB-EGF enhance the proliferation of programmable cells of monocytic origin (PCMO) through activation of MEK/ERK signaling and improve differentiation of PCMO-derived hepatocyte-like cells
por: Hyder, Ayman, et al.
Publicado: (2012)

A Mouse Model of Otitis Media Identifies HB-EGF as a Mediator of Inflammation-Induced Mucosal Proliferation
por: Suzukawa, Keigo, et al.
Publicado: (2014)

Targeting autocrine HB-EGF signaling with specific ADAM12 inhibition using recombinant ADAM12 prodomain
por: Miller, Miles A., et al.
Publicado: (2015)

Involvement of HB-EGF/Ascl1/Lin28a Genes in Dedifferentiation of Adult Mammalian Müller Glia
por: Stanchfield, Megan L., et al.
Publicado: (2020)

HB-EGF-induced IL-8 secretion from airway epithelium leads to lung fibroblast proliferation and migration
por: Li, Yanyu, et al.
Publicado: (2021)

Aloysia Citrodora Essential Oil Inhibits Melanoma Cell Growth and Migration by Targeting HB-EGF-EGFR Signaling
por: Salama, Yousef, et al.
Publicado: (2021)

Spinal cord repair is modulated by the neurogenic factor Hb-egf under direction of a regeneration-associated enhancer
por: Cigliola, Valentina, et al.
Publicado: (2023)

Identification of Heparin-Binding EGF-Like Growth Factor (HB-EGF) as a Biomarker for Lysophosphatidic Acid Receptor Type 1 (LPA(1)) Activation in Human Breast and Prostate Cancers
por: David, Marion, et al.
Publicado: (2014)

HB-EGF Activates the EGFR/HIF-1α Pathway to Induce Proliferation of Arsenic-Transformed Cells and Tumor Growth
por: Wang, Lin, et al.
Publicado: (2020)

HB-EGF Improves the Hair Regenerative Potential of Adipose-Derived Stem Cells via ROS Generation and Hck Phosphorylation
por: Choi, Nahyun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_kn7mtpqha7tbavrs0hief6sc20