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Structure–function relationships of peptides forming the calcin family of ryanodine receptor ligands

Calcins are a novel family of scorpion peptides that bind with high affinity to ryanodine receptors (RyRs) and increase their activity by inducing subconductance states. Here, we provide a comprehensive analysis of the structure–function relationships of the eight calcins known to date, based on the...

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Detalles Bibliográficos
Autores principales: Xiao, Liang, Gurrola, Georgina B., Zhang, Jing, Valdivia, Carmen R., SanMartin, Mario, Zamudio, Fernando Z., Zhang, Liming, Possani, Lourival D., Valdivia, Héctor H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845687/
https://www.ncbi.nlm.nih.gov/pubmed/27114612
http://dx.doi.org/10.1085/jgp.201511499