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RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner

Both RNF4 and KAP1 play critical roles in the response to DNA double-strand breaks (DSBs), but the functional interplay of RNF4 and KAP1 in regulating DNA damage response remains unclear. We have previously demonstrated the recruitment and degradation of KAP1 by RNF4 require the phosphorylation of S...

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Detalles Bibliográficos
Autores principales: Kuo, Ching-Ying, Li, Xu, Stark, Jeremy M., Shih, Hsiu-Ming, Ann, David K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845925/
https://www.ncbi.nlm.nih.gov/pubmed/26766492
http://dx.doi.org/10.1080/15384101.2016.1138184