Periodic expression of Kv10.1 driven by pRb/E2F1 contributes to G2/M progression of cancer and non-transformed cells

Progression of cell cycle is associated with changes in K(+) channel expression and activity. In this study, we report that Kv10.1, a K(+) channel that increases cell proliferation and tumor growth, is regulated at the transcriptional level by the pRb/E2F1 pathway. De-repression of E2F1 by HPV-E7 on...

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Detalles Bibliográficos
Autores principales: Urrego, Diana, Movsisyan, Naira, Ufartes, Roser, Pardo, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845928/
https://www.ncbi.nlm.nih.gov/pubmed/27029528
http://dx.doi.org/10.1080/15384101.2016.1138187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845928/
https://www.ncbi.nlm.nih.gov/pubmed/27029528
http://dx.doi.org/10.1080/15384101.2016.1138187

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