A Geometrically-Constrained Mathematical Model of Mammary Gland Ductal Elongation Reveals Novel Cellular Dynamics within the Terminal End Bud

Mathematics is often used to model biological systems. In mammary gland development, mathematical modeling has been limited to acinar and branching morphogenesis and breast cancer, without reference to normal duct formation. We present a model of ductal elongation that exploits the geometrically-con...

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Detalles Bibliográficos
Autores principales: Paine, Ingrid, Chauviere, Arnaud, Landua, John, Sreekumar, Amulya, Cristini, Vittorio, Rosen, Jeffrey, Lewis, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845990/
https://www.ncbi.nlm.nih.gov/pubmed/27115287
http://dx.doi.org/10.1371/journal.pcbi.1004839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845990/
https://www.ncbi.nlm.nih.gov/pubmed/27115287
http://dx.doi.org/10.1371/journal.pcbi.1004839

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