Cargando…

A Geometrically-Constrained Mathematical Model of Mammary Gland Ductal Elongation Reveals Novel Cellular Dynamics within the Terminal End Bud

Mathematics is often used to model biological systems. In mammary gland development, mathematical modeling has been limited to acinar and branching morphogenesis and breast cancer, without reference to normal duct formation. We present a model of ductal elongation that exploits the geometrically-con...

Descripción completa

Detalles Bibliográficos
Autores principales:	Paine, Ingrid, Chauviere, Arnaud, Landua, John, Sreekumar, Amulya, Cristini, Vittorio, Rosen, Jeffrey, Lewis, Michael T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845990/ https://www.ncbi.nlm.nih.gov/pubmed/27115287 http://dx.doi.org/10.1371/journal.pcbi.1004839

Ejemplares similares

STAT5 deletion in macrophages alters ductal elongation and branching during mammary gland development
por: Brady, Nicholas J., et al.
Publicado: (2017)

Mathematical Oncology: How Are the Mathematical and Physical Sciences Contributing to the War on Breast Cancer?
por: Chauviere, Arnaud H., et al.
Publicado: (2010)

Identification of stem cell units in the terminal end bud and duct of the mouse mammary gland
por: Kenney, Nicholas J, et al.
Publicado: (2001)

The histone demethylase Kdm3a is required for normal epithelial proliferation, ductal elongation and tumor growth in the mouse mammary gland
por: Qin, Li, et al.
Publicado: (2017)

Key stages in mammary gland development: The mammary end bud as a motile organ
por: Hinck, Lindsay, et al.
Publicado: (2005)

Tumors of the mammary gland
por: Rosen, Paul Peter
Publicado: (1993)

Ductal Macrophages Predominate in the Immune Landscape of the Lactating Mammary Gland
por: Hassel, Chervin, et al.
Publicado: (2021)

Mechanical plasticity of collagen directs branch elongation in human mammary gland organoids
por: Buchmann, B., et al.
Publicado: (2021)

ErbB3 is required for ductal morphogenesis in the mouse mammary gland
por: Jackson-Fisher, Amy J, et al.
Publicado: (2008)

Loss of sfrp1 promotes ductal branching in the murine mammary gland
por: Gauger, Kelly J, et al.
Publicado: (2012)

The Terminal End Bud: the Little Engine that Could
por: Paine, Ingrid S., et al.
Publicado: (2017)

Key stages in mammary gland development: The cues that regulate ductal branching morphogenesis
por: Sternlicht, Mark D
Publicado: (2006)

Ductal Architecture: Corrosion Casting of Canine Mammary Glands Using an Intraductal Approach
por: Kolasinac, Sabina Sibcic, et al.
Publicado: (2023)

Salvia officinalis L. induces alveolar bud growing in adult female rat mammary glands
por: Monsefi, Malihezaman, et al.
Publicado: (2015)

Geometrically constrained square pyramidal phosphoranide
por: Volodarsky, Solomon, et al.
Publicado: (2022)

Ectodysplasin target gene Fgf20 regulates mammary bud growth and ductal invasion and branching during puberty
por: Elo, Teresa, et al.
Publicado: (2017)

Spindle architecture constrains karyotype in budding yeast
por: Helsen, Jana, et al.
Publicado: (2023)

RARα1 control of mammary gland ductal morphogenesis and wnt1-tumorigenesis
por: Cohn, Ellen, et al.
Publicado: (2010)

Activation of retinoblastoma protein in mammary gland leads to ductal growth suppression, precocious differentiation, and adenocarcinoma
por: Jiang, Zhe, et al.
Publicado: (2002)

Pregnancy-induced changes in cell-fate in the mammary gland
por: Ginger, Melanie R, et al.
Publicado: (2003)

Ductal barriers in mammary epithelium
por: Owens, Mark B, et al.
Publicado: (2013)

Keratin 6 is not essential for mammary gland development
por: Grimm, Sandra L, et al.
Publicado: (2006)

Parathyroid Hormone-Related Protein Is Not Required for Normal Ductal or Alveolar Development in the Post-Natal Mammary Gland
por: Boras-Granic, Kata, et al.
Publicado: (2011)

Loss of caveolin-1 alters extracellular matrix protein expression and ductal architecture in murine mammary glands
por: Thompson, Christopher, et al.
Publicado: (2017)

Utility of Tissue Classification in Invasive Ductal Carcinoma using Dynamic Magnetic Resonance Imaging of the Mammary Gland
por: Miyazaki, Yoshiaki, et al.
Publicado: (2021)

A Novel, Patient-Specific Mathematical Pathology Approach for Assessment of Surgical Volume: Application to Ductal Carcinoma in situ of The Breast
por: Edgerton, Mary E., et al.
Publicado: (2011)

Dual Reactivity of a Geometrically Constrained Phosphenium Cation
por: Volodarsky, Solomon, et al.
Publicado: (2022)

Mammary gland neoplasia.
por: Neumann, D A, et al.
Publicado: (1996)

Tuberculosis of the Mammary Gland
por: Goyle, Amar Nath, et al.
Publicado: (1935)

Tumor in Mammary Gland
Publicado: (1872)

Epithelial and non-epithelial Ptch1 play opposing roles to regulate proliferation and morphogenesis of the mouse mammary gland
por: Monkkonen, Teresa, et al.
Publicado: (2017)

Geometric tumor embolic budding characterizes inflammatory breast cancer
por: Modi, Arnav P., et al.
Publicado: (2022)

Geometric control of myosin II orientation during axis elongation
por: Lefebvre, Matthew F, et al.
Publicado: (2023)

Rule-based spatial modeling with diffusing, geometrically constrained molecules
por: Gruenert, Gerd, et al.
Publicado: (2010)

Mammary stem cells: angels or demons in mammary gland?
por: Chen, Xueman, et al.
Publicado: (2017)

Scribble Modulates the MAPK/Fra1 Pathway to Disrupt Luminal and Ductal Integrity and Suppress Tumour Formation in the Mammary Gland
por: Godde, Nathan J., et al.
Publicado: (2014)

Pubertal exposure to dietary advanced glycation end products disrupts ductal morphogenesis and induces atypical hyperplasia in the mammary gland
por: Krisanits, Bradley A., et al.
Publicado: (2023)

Tumour buds determine prognosis in resected pancreatic ductal adenocarcinoma
por: Lohneis, Philipp, et al.
Publicado: (2018)

Surgical Pathology of the Mammary Gland
Publicado: (1934)

Epigenomics of mammary gland development
por: Holliday, Holly, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_burq6q81ljn434qm9jgj4ajica