5-Hydroxy-7-Methoxyflavone Triggers Mitochondrial-Associated Cell Death via Reactive Oxygen Species Signaling in Human Colon Carcinoma Cells

Plant-derived compounds are an important source of clinically useful anti-cancer agents. Chrysin, a biologically active flavone found in many plants, has limited usage for cancer chemotherapeutics due to its poor oral bioavailability. 5-Hydroxy-7-methoxyflavone (HMF), an active natural chrysin deriv...

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Detalles Bibliográficos
Autores principales: Bhardwaj, Monika, Kim, Na-Hyung, Paul, Souren, Jakhar, Rekha, Han, Jaehong, Kang, Sun Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846015/
https://www.ncbi.nlm.nih.gov/pubmed/27116119
http://dx.doi.org/10.1371/journal.pone.0154525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846015/
https://www.ncbi.nlm.nih.gov/pubmed/27116119
http://dx.doi.org/10.1371/journal.pone.0154525

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