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5-Hydroxy-7-Methoxyflavone Triggers Mitochondrial-Associated Cell Death via Reactive Oxygen Species Signaling in Human Colon Carcinoma Cells
Plant-derived compounds are an important source of clinically useful anti-cancer agents. Chrysin, a biologically active flavone found in many plants, has limited usage for cancer chemotherapeutics due to its poor oral bioavailability. 5-Hydroxy-7-methoxyflavone (HMF), an active natural chrysin deriv...
Autores principales: | Bhardwaj, Monika, Kim, Na-Hyung, Paul, Souren, Jakhar, Rekha, Han, Jaehong, Kang, Sun Chul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846015/ https://www.ncbi.nlm.nih.gov/pubmed/27116119 http://dx.doi.org/10.1371/journal.pone.0154525 |
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