Constraints on Biological Mechanism from Disease Comorbidity Using Electronic Medical Records and Database of Genetic Variants

Patterns of disease co-occurrence that deviate from statistical independence may represent important constraints on biological mechanism, which sometimes can be explained by shared genetics. In this work we study the relationship between disease co-occurrence and commonly shared genetic architecture...

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Detalles Bibliográficos
Autores principales: Bagley, Steven C., Sirota, Marina, Chen, Richard, Butte, Atul J., Altman, Russ B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846031/
https://www.ncbi.nlm.nih.gov/pubmed/27115429
http://dx.doi.org/10.1371/journal.pcbi.1004885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846031/
https://www.ncbi.nlm.nih.gov/pubmed/27115429
http://dx.doi.org/10.1371/journal.pcbi.1004885

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