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Monocyte Trafficking, Engraftment, and Delivery of Nanoparticles and an Exogenous Gene into the Acutely Inflamed Brain Tissue – Evaluations on Monocyte-Based Delivery System for the Central Nervous System

The ability of monocytes and monocyte-derived macrophages (MDM) to travel towards chemotactic gradient, traverse tissue barriers, and accumulate precisely at diseased sites makes them attractive candidates as drug carriers and therapeutic gene delivery vehicles targeting the brain, where treatments...

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Detalles Bibliográficos
Autores principales: Tong, Hsin-I, Kang, Wen, Davy, Philip M. C., Shi, Yingli, Sun, Si, Allsopp, Richard C., Lu, Yuanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846033/
https://www.ncbi.nlm.nih.gov/pubmed/27115998
http://dx.doi.org/10.1371/journal.pone.0154022