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Monocyte Trafficking, Engraftment, and Delivery of Nanoparticles and an Exogenous Gene into the Acutely Inflamed Brain Tissue – Evaluations on Monocyte-Based Delivery System for the Central Nervous System
The ability of monocytes and monocyte-derived macrophages (MDM) to travel towards chemotactic gradient, traverse tissue barriers, and accumulate precisely at diseased sites makes them attractive candidates as drug carriers and therapeutic gene delivery vehicles targeting the brain, where treatments...
Autores principales: | Tong, Hsin-I, Kang, Wen, Davy, Philip M. C., Shi, Yingli, Sun, Si, Allsopp, Richard C., Lu, Yuanan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846033/ https://www.ncbi.nlm.nih.gov/pubmed/27115998 http://dx.doi.org/10.1371/journal.pone.0154022 |
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