High-dose oral N-acetylcysteine fails to improve respiratory health status in patients with chronic obstructive pulmonary disease and chronic bronchitis: a randomized, placebo-controlled trial

BACKGROUND: Clinical outcomes are worse in patients with COPD and chronic bronchitis. N-acetylcysteine (NAC) is commonly prescribed for such patients but with uncertain clinical benefits. We postulated that oral NAC, at much larger doses than those ordinarily prescribed, would improve clinical outco...

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Detalles Bibliográficos
Autores principales: Johnson, Kara, McEvoy, Charlene E, Naqvi, Sakina, Wendt, Chris, Reilkoff, Ronald A, Kunisaki, Ken M, Wetherbee, Erin E, Nelson, David, Tirouvanziam, Rabindra, Niewoehner, Dennis E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846045/
https://www.ncbi.nlm.nih.gov/pubmed/27143871
http://dx.doi.org/10.2147/COPD.S102375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846045/
https://www.ncbi.nlm.nih.gov/pubmed/27143871
http://dx.doi.org/10.2147/COPD.S102375

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