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Comparison of KRAS and PIK3CA gene status between primary tumors and paired metastases in colorectal cancer
PURPOSE: In metastatic or recurrent colorectal cancer (MRCRC), the concordance of Kirsten rat sarcoma viral oncogene homolog (KRAS) and phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) mutation status between the primary tumors and metastases is still controversial. Th...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846063/ https://www.ncbi.nlm.nih.gov/pubmed/27143928 http://dx.doi.org/10.2147/OTT.S97668 |