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Comparison of KRAS and PIK3CA gene status between primary tumors and paired metastases in colorectal cancer

PURPOSE: In metastatic or recurrent colorectal cancer (MRCRC), the concordance of Kirsten rat sarcoma viral oncogene homolog (KRAS) and phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) mutation status between the primary tumors and metastases is still controversial. Th...

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Detalles Bibliográficos
Autores principales: He, Qiong, Xu, Qi, Wu, Wei, Chen, Lei, Sun, Weijing, Ying, Jieer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846063/
https://www.ncbi.nlm.nih.gov/pubmed/27143928
http://dx.doi.org/10.2147/OTT.S97668