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A First Tetraplex Assay for the Simultaneous Quantification of Total α-Synuclein, Tau, β-Amyloid(42) and DJ-1 in Human Cerebrospinal Fluid

The quantification of four distinct proteins (α-synuclein, β-amyloid(1-42), DJ-1, and total tau) in cerebrospinal fluid (CSF) has been proposed as a laboratory-based platform for the diagnosis of Parkinson’s disease (PD) and Alzheimer’s disease (AD). While there is some clinical utility in measuring...

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Detalles Bibliográficos
Autores principales: Kruse, Niels, Schlossmacher, Michael G., Schulz-Schaeffer, Walter J., Vanmechelen, Eugeen, Vanderstichele, Hugo, El-Agnaf, Omar M., Mollenhauer, Brit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846093/
https://www.ncbi.nlm.nih.gov/pubmed/27116005
http://dx.doi.org/10.1371/journal.pone.0153564