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Small molecule inhibitors of IRES-mediated translation

Many genes controlling cell proliferation and survival (those most important to cancer biology) are now known to be regulated specifically at the translational (RNA to protein) level. The internal ribosome entry site (IRES) provides a mechanism by which the translational efficiency of an individual...

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Detalles Bibliográficos
Autores principales: Vaklavas, Christos, Meng, Zheng, Choi, Hyoungsoo, Grizzle, William E, Zinn, Kurt R, Blume, Scott W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846101/
https://www.ncbi.nlm.nih.gov/pubmed/26177060
http://dx.doi.org/10.1080/15384047.2015.1071729