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17β-Estradiol Protects Rat Annulus Fibrosus Cells Against Apoptosis via α(1) Integrin-Mediated Adhesion to Type I Collagen: An In-vitro Study
BACKGROUND: 17β-Estradiol (E2) has been reported to protect annulus fibrosus (AF) cells in vitro against interleukin-1β (IL-1β)-induced apoptosis in a concentration-dependent manner. However, its time-response effect remains unexplored. In addition, integrin α(2)/collagen II interaction has been rep...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846184/ https://www.ncbi.nlm.nih.gov/pubmed/27108411 http://dx.doi.org/10.12659/MSM.897906 |