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Gα(s) regulates the post-endocytic sorting of G protein-coupled receptors

The role of Gα(s) in G protein-coupled receptor (GPCR) signalling at the cell surface is well established. Recent evidence has revealed the presence of Gα(s) on endosomes and its capacity to elicit GPCR-promoted signalling from this intracellular compartment. Here, we report an unconventional role f...

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Detalles Bibliográficos
Autores principales: Rosciglione, Stéphanie, Thériault, Caroline, Boily, Marc-Olivier, Paquette, Marilène, Lavoie, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846350/
https://www.ncbi.nlm.nih.gov/pubmed/25089012
http://dx.doi.org/10.1038/ncomms5556