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Regulation of cell protrusions by small GTPases during fusion of the neural folds

Epithelial fusion is a crucial process in embryonic development, and its failure underlies several clinically important birth defects. For example, failure of neural fold fusion during neurulation leads to open neural tube defects including spina bifida. Using mouse embryos, we show that cell protru...

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Detalles Bibliográficos
Autores principales: Rolo, Ana, Savery, Dawn, Escuin, Sarah, de Castro, Sandra C, Armer, Hannah EJ, Munro, Peter MG, Molè, Matteo A, Greene, Nicholas DE, Copp, Andrew J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846376/
https://www.ncbi.nlm.nih.gov/pubmed/27114066
http://dx.doi.org/10.7554/eLife.13273