Disruption of glycolytic flux is a signal for inflammasome signaling and pyroptotic cell death

When innate immune cells such as macrophages are challenged with environmental stresses or infection by pathogens, they trigger the rapid assembly of multi-protein complexes called inflammasomes that are responsible for initiating pro-inflammatory responses and a form of cell death termed pyroptosis...

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Detalles Bibliográficos
Autores principales: Sanman, Laura E, Qian, Yu, Eisele, Nicholas A, Ng, Tessie M, van der Linden, Wouter A, Monack, Denise M, Weerapana, Eranthie, Bogyo, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846378/
https://www.ncbi.nlm.nih.gov/pubmed/27011353
http://dx.doi.org/10.7554/eLife.13663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846378/
https://www.ncbi.nlm.nih.gov/pubmed/27011353
http://dx.doi.org/10.7554/eLife.13663

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