Early hyperactivity and precocious maturation of corticostriatal circuits in Shank3B(−/−) mice

Some autistic individuals exhibit abnormal development of the caudate nucleus and associative cortical areas, suggesting potential dysfunction of cortico-basal ganglia (BG) circuits. Using optogenetic and electrophysiological approaches in mice we identified a narrow postnatal period characterized b...

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Detalles Bibliográficos
Autores principales: Peixoto, Rui T., Wang, Wengang, Croney, Donyell M., Kozorovitskiy, Yevgenia, Sabatini, Bernardo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846490/
https://www.ncbi.nlm.nih.gov/pubmed/26928064
http://dx.doi.org/10.1038/nn.4260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846490/
https://www.ncbi.nlm.nih.gov/pubmed/26928064
http://dx.doi.org/10.1038/nn.4260

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