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Early hyperactivity and precocious maturation of corticostriatal circuits in Shank3B(−/−) mice
Some autistic individuals exhibit abnormal development of the caudate nucleus and associative cortical areas, suggesting potential dysfunction of cortico-basal ganglia (BG) circuits. Using optogenetic and electrophysiological approaches in mice we identified a narrow postnatal period characterized b...
Autores principales: | Peixoto, Rui T., Wang, Wengang, Croney, Donyell M., Kozorovitskiy, Yevgenia, Sabatini, Bernardo L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846490/ https://www.ncbi.nlm.nih.gov/pubmed/26928064 http://dx.doi.org/10.1038/nn.4260 |
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