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Chd7 Cooperates with Sox10 and Regulates the Onset of CNS Myelination and Remyelination

Mutations in CHD7, encoding ATP-dependent chromodomain-helicase-DNA-binding protein 7, in CHARGE syndrome leads to multiple congenital anomalies including craniofacial malformations, neurological dysfunction and growth delay. Currently, mechanisms underlying the CNS phenotypes remain poorly understo...

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Detalles Bibliográficos
Autores principales: He, Danyang, Marie, Corentine, Zhao, Chuntao, Kim, Bongwoo, Wang, Jincheng, Deng, Yaqi, Clavairoly, Adrien, Frah, Magali, Wang, Haibo, He, Xuelian, Hmidan, Hatem, Jones, Blaise V., Witte, David, Zalc, Bernard, Zhou, Xin, Choo, Daniel I., Martin, Donna M., Parras, Carlos, Lu, Q. Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846514/
https://www.ncbi.nlm.nih.gov/pubmed/26928066
http://dx.doi.org/10.1038/nn.4258