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PK‐PD modeling of individual lesion FDG‐PET response to predict overall survival in patients with sunitinib‐treated gastrointestinal stromal tumor

Pharmacometric models were developed to characterize the relationships between lesion‐level tumor metabolic activity, as assessed by the maximum standardized uptake value (SUV(max)) obtained on [(18)F]‐fluorodeoxyglucose (FDG) positron emission tomography (PET), tumor size, and overall survival (OS)...

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Detalles Bibliográficos
Autores principales: Schindler, E, Amantea, MA, Karlsson, MO, Friberg, LE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846778/
https://www.ncbi.nlm.nih.gov/pubmed/27299707
http://dx.doi.org/10.1002/psp4.12057