Dose Optimization of Efavirenz Based on Individual CYP2B6 Polymorphisms in Chinese Patients Positive for HIV

The purpose of this study was to investigate the impact of CYP2B6‐G516T polymorphisms on the pharmacokinetics (PKs) of efavirenz among the Chinese population and to propose doses for different genotypic populations that optimize therapeutic outcomes. Nonlinear mixed‐effect modeling was applied to de...

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Detalles Bibliográficos
Autores principales: Hui, KH, Lee, SS, Lam, TN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846779/
https://www.ncbi.nlm.nih.gov/pubmed/27299708
http://dx.doi.org/10.1002/psp4.12067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846779/
https://www.ncbi.nlm.nih.gov/pubmed/27299708
http://dx.doi.org/10.1002/psp4.12067

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