Cargando…

The Complexity of the ERK/MAP-Kinase Pathway and the Treatment of Melanoma Skin Cancer

The central role played by the ERK/MAPK pathway downstream of RAS in human neoplasias is best exemplified in the context of melanoma skin cancer. Signaling through the MAPK pathway is crucial for the proliferation of melanocytes, the healthy pigment cells that give rise to melanoma. However, hyper-a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wellbrock, Claudia, Arozarena, Imanol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846800/
https://www.ncbi.nlm.nih.gov/pubmed/27200346
http://dx.doi.org/10.3389/fcell.2016.00033