FET proteins regulate lifespan and neuronal integrity

The FET protein family includes FUS, EWS and TAF15 proteins, all of which have been linked to amyotrophic lateral sclerosis, a fatal neurodegenerative disease affecting motor neurons. Here, we show that a reduction of FET proteins in the nematode Caenorhabditis elegans causes synaptic dysfunction ac...

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Detalles Bibliográficos
Autores principales: Therrien, Martine, Rouleau, Guy A., Dion, Patrick A., Parker, J. Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846834/
https://www.ncbi.nlm.nih.gov/pubmed/27117089
http://dx.doi.org/10.1038/srep25159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846834/
https://www.ncbi.nlm.nih.gov/pubmed/27117089
http://dx.doi.org/10.1038/srep25159

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