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The Amino Acid Substitution Q65H in the 2C Protein of Swine Vesicular Disease Virus Confers Resistance to Golgi Disrupting Drugs

Swine vesicular disease virus (SVDV) is a porcine pathogen and a member of the species Enterovirus B within the Picornaviridae family. Brefeldin A (BFA) is an inhibitor of guanine nucleotide exchange factors of Arf proteins that induces Golgi complex disassembly and alters the cellular secretory pat...

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Detalles Bibliográficos
Autores principales: Vázquez-Calvo, Ángela, Caridi, Flavia, González-Magaldi, Mónica, Saiz, Juan-Carlos, Sobrino, Francisco, Martín-Acebes, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846857/
https://www.ncbi.nlm.nih.gov/pubmed/27199941
http://dx.doi.org/10.3389/fmicb.2016.00612