Differential utilization of binding loop flexibility in T cell receptor ligand selection and cross-reactivity

Complementarity determining region (CDR) loop flexibility has been suggested to play an important role in the selection and binding of ligands by T cell receptors (TCRs) of the cellular immune system. However, questions remain regarding the role of loop motion in TCR binding, and crystallographic st...

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Detalles Bibliográficos
Autores principales: Ayres, Cory M., Scott, Daniel R., Corcelli, Steven A., Baker, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846865/
https://www.ncbi.nlm.nih.gov/pubmed/27118724
http://dx.doi.org/10.1038/srep25070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846865/
https://www.ncbi.nlm.nih.gov/pubmed/27118724
http://dx.doi.org/10.1038/srep25070

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