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Differential utilization of binding loop flexibility in T cell receptor ligand selection and cross-reactivity
Complementarity determining region (CDR) loop flexibility has been suggested to play an important role in the selection and binding of ligands by T cell receptors (TCRs) of the cellular immune system. However, questions remain regarding the role of loop motion in TCR binding, and crystallographic st...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846865/ https://www.ncbi.nlm.nih.gov/pubmed/27118724 http://dx.doi.org/10.1038/srep25070 |