Cargando…

Generation of exogenous germ cells in the ovaries of sterile NANOS3-null beef cattle

Blastocyst complementation (BC) systems have enabled in vivo generation of organs from allogeneic pluripotent cells, compensating for an empty germ cell niche in gene knockout (KO) animals. Here, we succeeded in producing chimeric beef cattle (Wagyu) by transferring allogenic germ cells into ovaries...

Descripción completa

Detalles Bibliográficos
Autores principales: Ideta, Atsushi, Yamashita, Shiro, Seki-Soma, Marie, Yamaguchi, Ryosaku, Chiba, Shiori, Komaki, Haruna, Ito, Tetsuya, Konishi, Masato, Aoyagi, Yoshito, Sendai, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4846992/
https://www.ncbi.nlm.nih.gov/pubmed/27117862
http://dx.doi.org/10.1038/srep24983